Need a simple comparison between sildenafil (Viagra) and tadalafil (Cialis)? Both treat erectile dysfunction by blocking PDE5, but they behave differently. Knowing how fast they work, how long they last, and what side effects to expect makes picking one easier. Below I break down the facts without jargon.
Start time: sildenafil usually works within 30–60 minutes; plan sex around that window. Tadalafil often shows effect in about 30 minutes as well for some men, but can take up to 2 hours for others.
Lasting power: sildenafil’s effects typically last about 4–6 hours. Tadalafil can last up to 36 hours — that’s why people call it the “weekend pill.” If you want spontaneity, tadalafil’s long window is useful.
Common doses: sildenafil commonly comes in 25, 50, and 100 mg. Tadalafil is available in 2.5, 5, 10, and 20 mg; 2.5–5 mg can be taken daily for ongoing effect, while 10–20 mg are used as needed.
Side effects overlap: headache, flushing, nasal congestion, and indigestion are common with both. Sildenafil is more likely to cause temporary visual changes (blue tint). Tadalafil sometimes causes muscle or back pain.
Food and alcohol: a high-fat meal can slow sildenafil’s absorption and delay its effect. Tadalafil is less affected by food, so it’s a bit more forgiving. Heavy drinking reduces effectiveness and raises dizziness risk for both.
Major interactions: never use either drug with nitrates (found in some chest pain meds) — that can cause a dangerous drop in blood pressure. Be cautious with alpha-blockers and some blood pressure medicines; check with your doctor.
Other uses: sildenafil also treats pulmonary hypertension (different dosing and brand). Tadalafil is approved for both ED and benign prostatic hyperplasia (BPH), which may help guys with urinary symptoms.
So which one fits you? If you prefer planning and a short window, sildenafil may work. If you want more spontaneity or a daily option, tadalafil could be better. If you have heart disease, take nitrates, or use multiple blood pressure drugs — talk to your clinician first.
Buying safely: always use a licensed pharmacy and keep a valid prescription. If ordering online, confirm the pharmacy’s credentials and read reviews. Fake meds can be dangerous.
Questions about timing, dose adjustments, or side effects? Ask your doctor — they can match the right drug to your health, other meds, and lifestyle.
